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Most chemical and herbal remedies, including the hormone melatonin, have not been tested nor approved by official agencies such as the United States Food and Drug Administration
Few studies have tested the use of melatonin for jet lag and have given mixed results, likely because the timing of administration needs to be precise and individualized.
Melatonin is present in the bloodstream naturally in differing amounts according to the time of day
It is produced by the pineal gland in darkness; secretion stops when there is light to the eyes
It plays a key role in the circadian rhythm which regulates various significant body functions.
A 2005 study showed that melatonin was effective in helping people fall asleep at doses of 0.3 milligrams (mg)
Then, to treat the jet lag, the recommended dose of melatonin is of 0.3 to 0.5 mg., to be taken the first day of traveling
Administration of higher doses can cause sleepiness, lethargy, confusion, and decreased mental sharpness.
Melatonin is not recommended for people with the symptoms of severe mental illness, severe allergies, autoimmune diseases, or immune system cancers
Neither is it recommended for pregnant women.
A recent study in hamsters showed that sildenafil citrate (known commercially as Viagra) aided in a 50% faster recovery from shifts comparable to eastward travel experienced by humans and was effective starting at low doses.
However, this use has not been tested in humans and is considered an off-label use by the drug's manufacturers.
The Weltzeituhr at Alexanderplatz in Berlin
For Jens Olsen's World Clock, which is actually an astronomical clock, see Jens Olsen's World Clock
A world clock, often called a "Worldtime Clock", is a clock which displays the time for many (or all) places around the world.
The clock face can incorporate multiple round analogue clocks with moving hands or multiple digital clocks with numeric readouts, with each clock being labelled with the name of a major city or time zone in the world.
It could also be a picture map of the world with inbedded analog or digital time-displays.
A moving circular map of the world, rotating inside a stationary 24 hour dial ring
Alternatively, the disc can be stationary and the ring moving.
Light projection onto a map representing daytime, used in the Geochron, a brand of a particular form or world clock.